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6/12/14 The TBIcare story Read more » 6/12/14 European Commission's Press Release on TBIcare Read more » 6/11/14 TBIcare on Euronews Read more »

Project Internal Pages

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Contact Information

Scientific Coordinator
Mark van Gils
VTT Technical Research Centre of Finland
P.O. Box 1300
33101 Tampere
Finland
tel. +358 20 722 3342
mark.vangils@vtt.fi

Project Manager
Harri Siitari
VTT Technical Research Centre of Finland
P.O. Box 106
20521 Turku
Finland
tel. +358 40 078 4517
harri.siitari@vtt.fi


Journal Papers

Juha Koikkalainen, Harri Pölönen, Jussi Mattila, Mark van Gils, Hilkka Soininen, Jyrki Lötjönen, for the Alzheimer’s Disease Neuroimaging Initiative. Improved Classification of Alzheimer’s Disease Data via Removal of Nuisance Variability. PLoS ONE 7(2): e31112, 2012.

A. Ragauskas, V. Matijosaitis, R. Zakelis, K. Petrikonis, D. Rastenyte, I. Piper, G. Daubaris. Clinical assessment of non-invasive intracranial pressure absolute value measurement methodNeurology, 78:1684-1691, May 22, 2012 .

M. Hartonen, I. Mattila, A.-L. Ruskeepää, M. Orešič, T. Hyötyläinen, Characterization of cerebrospinal fluid by comprehensive two-dimensional gas chromatography coupled to time-of-flight mass spectrometry, J. Chromatogr. A1293, 142-149, 2013

Arminas Ragauskas, Laimonas Bartusis, Ian Piper, Rolandas Zakelis, Vaidas Matijosaitis, Kestutis Petrikonis, Daiva Rastenyte. Improved diagnostic value of a TCD based non-invasive ICP measurement method compared with the sonographic ONSD method for detecting elevated intracranial pressure, Accepted for publication in Neurological Research, 2014.

 

Peer-reviewed Conference Papers

Christian Ledig, Robin Wolz, Paul Aljabar, Jyrki Lötjönen, Rolf A. Heckemann, Alexander Hammers, Daniel Rueckert. Multi-Class Brain Segmentation using Atlas Propagation and EM-Based Refinement. Proceedings of IEEE International Symposium on Biomedical Imaging (ISBI), Barcelona, Spain, 2012.

J Lötjönen, J Mattila, A Simonsen, M van Gils, J Koikkalainen, L Thurfjell, D Menon, O Tenovuo, G Waldemar, H Soininen. Generic evidence-based disease profiling for predicting outcomes: Application to Alzheimer’s disease and Traumatic Brain Injuries. In Proceedings of The Virtual Physiological Human 2012 (VPH2012), London, 2012

M. Jorge Cardoso, Robin Wolz, Marc Modat, Nick C. Fox, Daniel Rueckert, and Sebastien Ourselin. Geodesic Information Flows. In Proceedings of 15th International Conference on Medical Image Computing and Computer Assisted Intervention (MICCAI 2012), Nice, France, 2012.

K. K. Bhatia, A. Rao, A. N. Price, R. Wolz, J. Hajnal, D. Rueckert. Hierarchical manifold learning. In Proceedings of15th International Conference on Medical Image Computing and Computer Assisted Intervention (MICCAI 2012),  Nice, France, 2012.

C. Ledig, R.A. Heckemann, P. Aljabar, R. Wolz, J.V. Hajnal, A. Hammers, D. Rueckert. Segmentation of MRI brain scans using MALP-EM. In MICCAI 2012 Grand Challenge and Workshop on Multi-Atlas Labeling, pp. 79-82, 2012.

C. Ledig, R. Wolz, P. Aljabar, J. Lötjönen, D. Rueckert. PBSI: A symmetric probabilistic extension of the Boundary Shift Integral. In MICCAI 2012 Workshop on Novel Imaging Biomarkers for Alzheimer's Disease and Related Disorders (NIBAD'12), pp. 125-132, 2012.

 C. Ledig, R.A. Heckemann, D. Rueckert. Improving whole-brain multilabel segmentations through learned intensity-based statistical corrections.  SPIE Medical Imaging, 2013, Image Processing, 86691M, 2013.

Lötjönen, J., Ledig, C., Koikkalainen, J., Wolz, R., Thurfjell, L., Soininen, H., Ourselin, S., Rueckert, D., Extented Boundary Shift Integral. Accepted for publication in Proceedings of IEEE International Symposium on Biomedical Imaging (ISBI) 2014.

Ledig, C., Shi, W., Makropoulos, A., Koikkalainen, J., Heckemann, R. A., Hammers, A., Lötjönen, J., Tenovuo, O, Rueckert, D. Consistent and robust 4D whole-brain segmentation: application to traumatic brain injury. Accepted for publication in Proceedings of IEEE International Symposium on Biomedical Imaging (ISBI) 2014

Pszczolkowski, S., Zafeirou, S., Ledig, C., Rueckert, D., A Robust Similarity Measure for Nonrigid Image Registration with Outliers. Accepted for publication in Proceedings of IEEE International Symposium on Biomedical Imaging (ISBI) 2014.

Koikkalainen, J., Lötjönen, J., Ledig, C., Rueckert, D., Tenovuo, O., Menon, D., Fully Automatic Analysis of CT images for traumatic brain injury. Accepted for publication in Proceedings of IEEE International Symposium on Biomedical Imaging (ISBI) 2014.

Rao, A., Ledig, C., Newcombe, V., Menon, D., Rueckert, D., Contusion Segmentation from subjects with traumatic brain injury: a random forest framework. Accepted for publication in Proceedings of IEEE International Symposium on Biomedical Imaging (ISBI) 2014.

Peer-reviewed Abstracts

Olli Tenovuo, David Menon, Ari Katila, Jonathan Coles, Janek Frantzén and Joanna Outtrim - on behalf of the TBIcare collaborators. TBIcare – a new way to use traumatic brain injury biomarkers. In proceedings of National Neurotrauma Symposium 2011, Ft. Lauderdale, 2011.

Olli Tenovuo, David K. Menon, Ari Katila, Jonathan P. Coles, Janek Frantzén and Joanna Outtrim, on behalf of the TBIcare collaborators. TBIcare – a new way to use traumatic brain injury biomarkers. In proceedings of 2011 International scientific conference for Biochemical Markers of Brain Damage, Lund, Sweden, 2011.

Antti Tanner, Mika Sarkela, Antti Tolonen, Loretta Norton, Corrine Davies-Schninkel, Michael Sharpe, G. Bryan Young. A Novel Method for Automatic Detection and Visualization of Non-Convulsive Seizures in ICU. In proceedings of The 64th AAN Annual Meeting, 2012; 78 (Meeting Abstracts 1). P04.016, New Orleans, Louisiana, 2012.

Olli Tenovuo, David Menon, Ari Katila, Jonathan Coles, Janek Frantzén, Joanna Outtrim. TBIcare – a new way to use traumatic brain injury biomarkers. Proceedings of Ninth World Congress on Brain Injury, Edinburgh, 2012.

Olli Tenovuo, David Menon, Ari Katila, Jonathan Coles, Janek Frantzén, Joanna Outtrim. The International TBIcare Study – Preliminary Results. Proceedings of National Neurotrauma Symposium 2012, Phoenix, Arizona, 2012.

Ragauskas A, Zakelis R, Petkus V, Daubaris G, Bartusis L. Human brain in microgravity: how to measure intracranial pressure non-invasively? In Proceedings of 28th Annual Meeting of the American Society for Gravitational and Space Research, 2012.

Ragauskas A. How to measure intracranial pressure non-invasively. Proceedings of Asian Clinical Congress, Bangkok, Thailand, January 2013.

A.Ragauskas, L.Bartusis, R.Zakelis, G.Daubaris, V.Matijosaitis, K.Petrikonis, D.Rastenyte. Receiver operating characteristic analysis of noninvasive intracranial pressure measurement methods. Cerebrovasc Dis (Abstracts of 18th Meeting of the European Society of Neurosonology and Cerebral Hemodynamics), 35(suppl 1), p.72, 2013.

Olli Tenovuo, David Menon, Ari Katila, Jonathan Coles, Janek Frantzen, Jo Outtrim – on behalf of the TBIcare comsortium. TBIcare software as a clinical aid in brain injury medicineProceedings of National Neurotrauma Symposium 2013, Nashville TN, August 2013.

Janek Frantzen, Ari Katila, Riikka Takala, Henna Ala-Seppälä, Anna Kyllönen et al., Injury Profiles, demographic features and outcomes in 200 unselected consecutive adults with acute TBI attending a regional emergency care unit. Proceedings of Tenth World Congress on Brain Injury, San Francisco, CA, March 2014.

Olli Tenovuo, David Menon, Mark van Gils, Daniel Rueckert, Ari Katila et al., Improving the Individual Diagnostics of TBI – the International TBIcare project. Proceedings of Tenth World Congress on Brain Injury, San Francisco, CA, March 2014.

Jussi Posti, Tuulia Hyötyläinen et al., Blood metabolomic patterns correlate with the severity of traumatic brain injury. Proceedings of Tenth World Congress on Brain Injury, San Francisco, CA, March 2014.

 

Other

Harri Siitari and Olli Tenovuo – on behalf of the TBIcare consortium. TBIcare: Developing personalised solutions for the treatment of traumatic brain injury. Press release VTT and TUCH, 24 February 2011.

Mark van Gils and Olli Tenovuo. Developing personalised solutions for the treatment of traumatic brain injury:  The TBIcare project. Cybertherapy & Rehabilitation, 2011(1):34-35, 2011.

Mark van Gils. TBIcare: Evidence based Diagnostic and Treatment Planning Solution for Traumatic Brain Injuries. FP7 Resource book of eHealth projects, 2011.

Mark van Gils and Olli Tenovuo. The TBIcare project: Evidence-based Diagnostic and Treatment Planning Solution for Traumatic Brain Injuries. VPH Newsletter, 2011.

Olli Tenovuo and David Menon. The TBIcare project: Evidence based Diagnostic and Treatment Planning Solution for Traumatic Brain Injuries. IBIA International Neurotrauma Letter, February 2012.

D. Rueckert. Learning and Discovery of Clinically Useful Information from Medical Images. IEEE EMBS Grand Challenge Meeting, Washington, DC, February 2012.

Jyrki Lötjönen. Evidence-based data mining. Orion Pharma, Espoo, Finland, March 27, 2012.

Harri Siitari. VTT Technologies for health – tools for future personalized, pre-emptive and predictive health care. India – European Union / Member States Conference, The Indo-European Research and Innovation Partnership. Brussels, May 31 - June 1, 2012.

Harri Siitari. Integrated technology solutions for adding value in diagnostics. Biotechnology in Health and Disease. Turku, March 26-28, 2012.

Harri Siitari. Personalized solutions for the diagnosis of brain diseases. TuBS Summer School 2012. Turku, August 15, 2012.

C. Ledig. Multi-class brain segmentation and atrophy measurement using Expectation-Maximization. The Neurodis Foundation, Lyon, France, May 2012.

D. Rueckert, Learning and Discovery of Clinically Useful Information from Medical Images. Microsoft Research Cambridge, UK, May 2012.

D. Rueckert. Machine learning meets medical imaging: From signals to clinically useful information. Scientific Computing and Imaging Institute, University of Utah, September 2012.

C. Ledig. Structural atrophy measurement and multi-class segmentation on MR brain scans. VTT Technical Research Centre of Finland, Tampere, Finland, September 2012.

J Lötjönen, J Mattila, A Simonsen, M van Gils, J Koikkalainen, L Thurfjell, D Menon, O Tenovuo, G Waldemar, H Soininen. Visualizing the disease state fingerprint for predicting clinical outcomes: Application to Alzheimer’s disease and Traumatic Brain Injuries.  BioIT World Conference and Expo, Boston 8-9 April 2013.

M. van Gils. Decision support systems for neurosciencesCrosslinks Turku 2013 - Neuroscience, April 16, 2013.

M. van Gils. TBIcareeHealth and the Brain - ICT for Neuropsychiatric Health event organised by EC DG CONNECT, 5 November 2013.

Harri Siitari, Olli Tenovuo, David Menon, Jyrki Lötjönen, Jussi Mattila, Ari Katila, Daniel Rueckert, Matej Oresic, Peter Ylen, Mark van Gils. Several presentations in Proceedings of TTBIS2014 – TBIcare symposium (TBIcare public workshop), Turku, 17 January 2014.

David Menon, The GAIN study – construction and current views, Genetic Associations in Neurotrauma - The Gain symposium , Turku, 18 January 2014.